KuVitro Fertilization (IVF)

Kuyini ku- Vitro Fertilization (IVF)

I-'Vitro 'isuselwa kwelesiLatini, elithi' vitrum ', elisho ingilazi. 'I-in-vitro fertilization' (IVF) ngokwezwi nezwi isho ukuthi 'umanyolo engilazini', yingakho izingane ezivela kulokhu kwelashwa zivame ukubizwa ngokuthi 'ama-test tube baby'. Yakhiwa iminyaka engaphezu kwe-30 eyedlule ekwelashweni kwabesifazane abanamashubhu e-Fallopian owonakele, futhi lokhu kuseyisizathu esibalulekile sokwelashwa namuhla.

Ingane yokuqala ye-IVF emhlabeni uLouise Brown wazalwa e-1978 e-United Kingdom kwathi i-IVF yaba ukwelashwa okujwayelekile kokungazali kusukela ku-1983. Kusukela lapho, zingaphezu kwezigidi ezingama-5 izingane ezizelwe emhlabeni wonke futhi amazinga e-IVF empumelelo manje aqhathaniswa futhi aphakeme kunalawo wemvelo. UDkt Johan Van Schouwenburg weMedfem Fertility Clinic wenza i-IVF yokuqala eNingizimu Afrika noProfessor Kruger esibhedlela saseTygerberg e1983.


IVF isho inqubo yokwenziwa kabusha kosizo lapho iqanda nesidoda kuxhunyaniswa ngaphandle komzimba ukuze kwakhiwe umbungu. Le mbungu idluliselwa esibelethweni ukuze ifakwe ngethemba futhi ikhulelwe.

Zonke izindlela zokwelashwa ze-IVF ziqala ngenkambo yokwelashwa kwehomoni ukukhuthaza ukwakhiwa kwezilonda eziningana esibelethweni. Lezi bese zibhobozwa ngenaliti ekhethekile ngaphansi kokuqondiswa kwe-ultrasound ukuthola amaqanda, abese efakwa esitsheni se-petri ('in vitro') ukudala imibungu eminingana. Ngemuva kwezinsuku ezintathu kuya kweziyisihlanu ku-incubator, owodwa noma emibili yale mibungu idluliswa esithweni sangasese iye esibelethweni, lapho ukufakwa kwenzeka khona nokukhulelwa kuqala. Kodwa-ke, ku-IVF njengokucabanga okungokwemvelo, akuzona zonke izimila zombungu ezikhulelwayo, yingakho imibungu eseleyo iqandisiwe - ukuze kudluliswe ukulandela okulandelayo uma owokuqala ehluleka. Ukuqandisa manje sekuyingxenye ebalulekile yohlelo lonke lwe-IVF yomtholampilo.

I-Medfem Fertility Clinic isebenza ngezifiso ze-IVF zokukhuthaza ezisetshenziselwa isiguli ngasinye ngokuya ngezinto eziningi (ukuxilongwa kokuzala, iminyaka, isisindo / ukuphakama, umphumela womjikelezo wangaphambilini, umlando wangaphambi kokuzala). Umtholampilo wethu we-IVF uphatha iziguli ezingaphezu kwenkulungwane unyaka ngamunye ngamazinga empumelelo ahlala njalo ephakeme futhi ephezulu ngaphezu kwezilinganiso zezwe.

I-IVF ephansi yedosi

I-Low Dose IVF, i-IVF yokugqugquzela okuncane, ubuchwepheshe obusha futhi obuthuthukisiwe bokuzala (i-ART) obunikeza enye indlela emnene yokugqugquzela ama-ovari kokukhulelwa kwendabuko kwe-vitro (IVF). Ku-Low Dose IVF amaqanda esifazane avuselelwa kancane, kusetshenziswa ama-ovulation induction agents kanye / noma imithamo ephansi yama-gonadotropin (i-follicle stimulating hormone ne-luteinizing hormone), ukukhuthaza ukukhula kwenani elincane lamaqanda.

Le nqubo iyefana ne-IVF yendabuko, ngaphandle kokuthi inhloso ukudala imibungu embalwa kodwa esezingeni eliphakeme yokudlulisa. I-Low Dose IVF iphendula ukukhathazeka okubili okukhulu kuzo zombili iziguli nodokotela - izindleko nokwedlula ngokweqile. Izitayela zakamuva emkhakheni wenzalo zikhetha ukwenziwa kwe-ovulation okusebenzisa imishanguzo embalwa futhi kukhiqize imibungu esezingeni elincane kepha engcono kunokwenziwa kwe-ovulation esebenzisa imithamo ephakeme kakhulu yemithi. Ngamanye amagama, i-Low Dose IVF iyindlela ewusizo engasetshenziswa ukusiza abesifazane ukuthi bakhulelwe ngobungozi obuncane nezindleko eziphansi.

I-Low Dose IVF iyithuluzi elihle kakhulu le-ART elivala igebe phakathi kwe-Natural Cycle IVF ne-IVF yendabuko. Ngenkathi kumjikelezo we-IVF wemvelo akukho ukukhuthazwa kwe-ovari okwenziwayo (ayikho imishanguzo ethathwa ngomlomo kanye / noma ngomjovo), evame ukuletha kuphela amaqanda akhuliswe ngokwemvelo ayi-1-2 nombungu owodwa, ku-Low Dose IVF ukukhuthazwa kwe-ovarian "okuthambile" kuveza amaqanda ama-3-4 nemibungu engama-2-3, okwandisa ukusebenza kahle komjikelezo kakhulu. Ngenkathi ku-IVF yendabuko umthamo omkhulu wama-gonadotropin uvame ukusetshenziselwa ukukhulisa amaqanda / imibungu kusuka kumjikelezo owodwa, ku-Low Dose IVF yikhwalithi yeqanda nombungu ekhulisiwe kunenombolo.

Isetjenziswa nini i-IVF?

I-IVF ekuqaleni yenzelwe abesifazane abanamashubhu ama-fallopian avinjelwe noma amashubhu alahlekile futhi asasetshenziselwa ukwelapha lezi zimo. Iyasetshenziswa futhi lapho ukungazali kungeke kuchazwe futhi nangezimbangela ezilandelayo ze-ovulatory noma zokwakheka:

  • Izinkinga zomlomo wesibeletho
  • endometriosis
  • Ukwehluleka kwe-IUI
  • Ama-Fibroids
  • Isizathu sokuzala
  • Izinkinga ze-ovulation
  • I-Polycystic ovarian syndrome
  • Ukungasebenzi okungaqondakali

Izigaba ze-IVF

Ukuqala i-IVF kungaba isikhathi esijabulisayo kakhulu - kungenye isinyathelo esiseduze nokuba ngabazali. Ngokwemvelo uzozizwa unethemba ngomphumela ophumelelayo kepha futhi udinga ukuzilungiselela cishe izinyanga ezimbili zemithi, izinqubo eziningana nokuhlolwa. Izinga lempumelelo le-IVF liphezulu, kepha iningi labashadikazi imijikelezo yokwelashwa eminingi ingadingeka.

Izigaba eziyisisekelo ezithintekayo kwinqubo ye-IVF zichazwe ngezansi. Yonke inqubo kusukela kuqala ukukhuthazeka kwe-ovary kuya esigabeni sokudluliswa kwe-umbungu imvamisa kuthatha nje amasonto amathathu.

Ingcindezele kangakanani i-IVF

IVF akusiwona umcimbi owodwa kepha kunalokho uchungechunge lwezigaba okudingeka ukuba lolo ngalunye luqedwe ngaphambi kokubhekana nokulandelayo. Lokhu kungenza kube inqubo yokuchitha isikhathi kakhulu. Imibhangqwana ingahamba ngemizwelo ehlukahlukene. Imisipha ingasuka ethembeni iye ekwesabeni, kusuka enjabulweni iye ekudumazekeni. Abesifazane abaningi bachaza okuhlangenwe nakho kokubhekana nokungazali kanye nokwelashwa kwe-IVF njenge- “rollercoaster” engokomzwelo. Ungase uzizwe izikhathi zokudabuka okukhulu, ulaka noma ukuzihlukanisa ngalesi sikhathi. Ukuhlangenwe nakho kwakho nokuthi ubhekana kanjani kuzoncika enanini elikhulu lezinto ngazinye kufaka phakathi ubuntu bakho, inethiwekhi yakho yokusekela, ubudlelwano onabo nomlingani wakho, usabela kanjani emithini yokuzala kanye nobude nenani lemijikelezo ye-IVF obhekana nayo .

Kujwayelekile ukuzizwa ukhungathekile, kepha ungenza izinto eziningi ukunakekela inhlala-kahle yakho yokomoya. Kubalulekile ukuthi uzinike isikhathi sokuphumula futhi ululame kusuka kumjikelezo ngamunye wokwelashwa. Uzodinga ukwamukela ushintsho olulethwa yi-IVF emzimbeni wakho, ushintsho kumazinga wakho wamandla, futhi kufanele uzame ukunciphisa noma ukubeka phambili imisebenzi yakho ngokufanele.

IMedfem Fertility Clinic inikezela ngezinsizakalo zokweluleka inzalo ngozakwethu uDkt Mandy Rodrigues. Sincoma kakhulu ukuthi noma ngubani owenza umjikelezo we-IVF afune ukuxhaswa ngudokotela wezengqondo onolwazi nozwela ongazalisi. Amazinga okuncipha okwehlisiwe kanye nohlelo oluhle lokuxhaswa kuyaphawuleka ukwandisa umphumela omuhle wokukhulelwa.

Okuqhamuka uma udla imishanguzo

Umphumela obikwa kakhulu 'ohlangene' ohlotshaniswa ne-IVF ukukhulelwa okuningi. Kukhona ingozi encane kakhulu yokuthi abanye besifazane (1-2%) bazosabela ngokweqile emithini yezidakamizwa esetshenziselwa ukuvuselela ama-ovari, kepha ukuqapha kwe-ultrasound ne-hormone ngalesi sigaba sokwelashwa kwezidakamizwa ngokuvamile kuqinisekisa ukuthi noma yikuphi ukuphendula ngokweqile kubonakala kusengaphambili futhi noma iyiphi ingozi igwenyiwe. Ukuqoqwa kwamaqanda kungakhathazi, futhi kwenziwa nge-sedation eyazi. Kunqunywa ababulali abafanele bezinhlungu kubo bonke uma kunesidingo sokuthatha.

I-Ovarian Hyperstimulation Syndrome (OHSS) yisimo sezokwelapha esingandile kodwa esingabeka empilweni lapho kungenzeka ukuthi ama-ovary akho avuswe kakhulu yimithi yokuzala. Ama-ovari angakhuphuka ngosayizi futhi akhiqize uketshezi oluningi. Kubonakala ngobuhlungu nokuqhakaza esiswini sakho futhi uma i-sever ingadala izinkinga ngokuphefumula noma ngokuchama. Thintana nelungu leqembu lakho lokunakekelwa kwezempilo ngokushesha uma ukholelwa ukuthi unazo ezinye zalezi zimpawu.

Ukulungiselela Amathuba Akho

Isisindo: Kubalulekile ukuba nesisindo esinempilo sokuphakama kwakho. Abesifazane abanenkomba yomzimba ngaphansi kuka-19 noma ngaphezulu kwama-32 banethuba eliphansi lokukhulelwa kanye nengozi eyengeziwe yokukhulelwa kwesisu.

Ukubhema: Abesifazane ababhemayo banamathuba aphansi okukhulelwa nezinga eliphakeme lokuphuphuma kwesisu.

Izithasiselo: Sincoma ukuthi uthathe i-multivitamin equkethe i-folic acid (i-0.4 ukuya ku-1.0 mg nsuku zonke). Le vithamini ye-B inciphisa ubungozi bokulimala okuthile kobuchopho kanye nomgogodla ku-fetus.

Amanani okuphumelela

Njengolunye uhlobo lokwelashwa kokuzala, amazinga empumelelo ekwehleni kwe-IVF uma iziguli sezineminyaka yobudala engama-35 noma ngaphezulu. Ngaphambi kwalokho, amazinga okukhulelwa e-IVF eMedfem Fertility Clinic cishe angama-50%. Kubalulekile ukuqonda ukuthi impumelelo isho ukuthini futhi ngokujwayelekile manje sekusetshenziswa isilinganiso “sokubeletha”, ithuba lokuzala ingane enempilo. IMedfem Fertility Clinic inamazinga empumelelo ahambisana nokubikwa okuphezulu kakhulu emitholampilo emhlabeni jikelele.

Umsebenzi Welebhu

I-Intracytoplasmic isidoda sindano (i-ICSI) inqubo lapho isidoda esisodwa sifakwa eqandeni. I-ICSI intuthuko enkulu kunazo zonke ekwelashweni kokuzala kusukela i-in vitro fertilization (IVF) futhi ivumele amadoda amaningi ukuba abe nezingane ezihlobene nofuzo. Njengoba i-ICSI idinga isidoda esincane kakhulu, kungaba ukwelashwa okusebenzayo kwabesilisa abahlukunyezwa kakhulu isidoda. Imvamisa, i-ICSI isebenzisa isidoda esihunyushiwe emzimbeni, kepha isidoda esibuyiselwe ngamehlo singasetshenziswa futhi. I-ICSI yenziwa njengengxenye yomjikelezo we-IVF.

I-Laser Assisted Hatching: Enkambisweni ejwayelekile yokufakelwa umbungu kufanele unqamule isembozo sangaphandle esinjenge-gel esibizwa nge-zona pellucida ngaphambi kokunamathisela ku-endometrium. Eminye imibungu ingaba ne-zona pellucida eqinile kunezinye. Kungenzeka uvule okuncane ku-zona pellucida usebenzisa i-laser, ngaphambi nje kokudluliswa kombungu. Le ndlela ibizwa ngokuthi yi-laser assisted hatching. Kuyinto ejwayelekile eMedfem Clinic ezigulini ezingaphezulu kweminyaka engama-38.

Isiko le-Blastocyst lisetshenziselwa ukuthuthukisa ukukhula kwe-embus elebhu ngaphezu kwezinsuku ezintathu. Ngemuva kwezinsuku ezinhlanu kusiko, imibungu ifinyelela esigabeni sokuhlambalaza, lapho inamaseli angaphezu kwe-80 azungeze umgodi ogcwele uketshezi. Le nkathi ende yesiko le-umbungu ivumela ikhono elingcono lokukhetha imibungu enempilo kunazo zonke ukuze idluliselwe futhi ihlotshaniswa nezinga eliphakeme lokukhulelwa, ngenkathi kudluliswa imibungu embalwa.

I-embryo Vitrification: Imibungu engaphezulu ingahlala ngemuva komjikelezo wakho we-in vitro fertilization (IVF) kanye nokudluliselwa okusha kwe-umbungu. Le mibungu ingahle ilungele ukubekelwa amanzi noma ukuqhwa. I-embryo cryopreservation inikeza ithuba lemizamo eyengeziwe ekhulelwe ngesikhathi somjikelezo we-IVF owodwa. IVitrification iyindlela ekhethekile yokuqandisa lapho imibungu ibekwa khona kusetshenziswa inqubo yokupholisa ngokushesha, ukuyiguqula ibe yingilazi eqinile esikhundleni seqhwa, futhi ngokwenza lokho kugwema ukwakheka kwe-ice-crystal okungaba yingozi enkulu ekusindeni kwabo.


Izigaba ze-IVF

Isigaba 1: Ukugqugquzela nokuqapha kwe-Ovarian

Ekuqaleni komjikelezo wakho wokuya esikhathini i-hypothalamus ikhipha i-hormone ebizwa nge-gonadtrophin-releasing hormone (GnRH). I-GnRH yona idala ukuthi i-pituitary gland ikhiphe i-hormone ebizwa nge-follicle ivuselela i-hormone (FSH) ukulungiselela iqanda lokuthi likhishwe. Lapho iqanda selivuthiwe i-pituitary gland ikhiqiza enye i-hormone ebizwa nge-luteinising hormone (LH). Lokhu kuthuthukisa i-follicle ukukhipha iqanda ku-fallopian tube kwinqubo eyaziwa ngokuthi yi-ovulation. Ama-Fliclicle angama-skethi agcwele uketshezi lapho amaqanda ekhula khona ekuvuthweni.

Nge-IVF, eminye imishanguzo isetshenziselwa ukuvimba ukuphuma kwamaqanda ngenkathi eminye imishanguzo, okuyizinguqulo zokwenziwa ze-FSH, isetshenziselwa ukukhuthaza ama-ovaries ukwakha ama-follicle ama-ovarian more. Ngokuba namaqanda amaningi avuthiwe atholakalayo ngokuzama ukukhulelwa nokudluliswa kunethemba lokuthi okungenani elilodwa kuzoholela ekukhulelweni.

Esigabeni sokugqugquzelwa kwama-ovari, amaqanda akho akhiqizwa ukukhiqiza amaqanda amaningi kunokujwayelekile. Uzothatha imijovo yansuku zonke ye-luteinizing hormone (LH) ne-follicle ivuselela i-hormone (FSH) cishe nge-8 kuya ezinsukwini ze-10. Le mijovo yama-hormone izothuthukisa amaqanda akho ukukhiqiza ama-follicle amaningana, ngalinye lawo lingaba neqanda. Omunye wabahlengikazi bethu uzokufundisa ukuthi ungazinikeza kanjani imijovo.

Izinhlobo ezimbili zemithi zisetshenziswa ngalesi sigaba ukucindezela i-ovulation:

  • I-Cetrotide ingezwe njengomjovo ongaphansi kokukodwa lapho izingcezu zifika cishe nge-14mm ngosayizi kuphrothokholi ethandwa kakhulu. Lokhu kwaziwa njenge-protagonist protocol futhi iqala ngosuku lwesithathu lokuya esikhathini.
  • Ku-Long Course Protocol umuthi obizwa ngokuthi yiLucrin uqalwa ngokungazwisiseki kusukela osukwini lwamashumi amabili lokuqala lomjikelezo wokuya esikhathini ukuvimbela i-ovulation yezicucwana ezivuselelekile. Lapho inkathi iqala i-FSH ne-LH sebeqalile ukukhuthaza ukukhula kwama-follicle njengakwenye protocol.

Ngesikhathi sokuvuselelwa kwe-ovarian sisebenzisa i-ultrasound ukuqapha amaqanda akho, nokuhlolwa kwegazi ukukala amazinga we-estrogen yakho. Izikali ze-Ultrasound zenziwa ngemuva kwezinsuku ezinhlanu zokujova ama-hormone ukuthola inani lama-follicle nosayizi we-follicle. Akuwona wonke ama-follicle aqukethe amaqanda nosayizi we-follicle onquma ukuvuthwa kwamaqanda. Imvamisa ama-follicle mancane kuskena sokuqala, ukuskena okulandelayo kanye nokujova kwama-hormone kuzoqhubeka kuze kube yilapho ifulethi eliholayo lifinyelela ku-18mm noma ngaphezulu ngosayizi.

Umjovo we-Ovulation (Ovitrelle noma uLucrin) - Lo mjovo uvame ukunikezwa ngesikhathi esithile kusihlwa. Ukubuyisa amaqanda kuzobe sekwenzeka amahora angama-36 noma ngaphezulu ngemuva kokujova kwe-ovulation.

Uzoba nokuhlolwa kwakho kwe-ultrasound nokuhlolwa kwegazi eMedfem Fertility Clinic phakathi kwe-7: 00 am ne-9: 30 am ngoMsombuluko kuze kube uLwesihlanu, naphakathi kwe7: 30 am kanye ne9: 00 am ngezimpelasonto.

Isigaba 2: Ukubuyiselwa kweqanda (i-oocyte)

Lapho ukuhlolwa kwe-ultrasound nokuhlolwa kwegazi kukhombisa ukuthi unosayizi ofanele nenani lama-follicles, uzothatha umjovo we-hCG (i-human Chorionic Gonadotropin) ukuvusa ukuvuthwa kokugcina kwamaqanda. Ukubuyiselwa kweqanda kuhlelwe ngaphambi nje kwe-ovulation okulindelekile, imvamisa amahora we-36 ngemuva kokuphathwa kwezidakamizwa ezifaka i-ovulation. Udokotela wakho uzozama ukuthola amaqanda amaningi avuthiwe ngangokunokwenzeka.

Ukubuyiselwa kweqanda kwenziwa ngaphansi kokubulala izinzwa kwasendaweni, okuvame kakhulu ngenaliti eqondiswe kahle ye-ultrasound. Ama-follicle avuthiwe akhonjwe kusetshenziswa i-ultrasound, bese kudluliswa inaliti odongeni lwesitho sangasese sowesifazane bese kutholakala uketshezi olusuka ku-follicle oluvuthiwe ngokumunca ngobumnene. Uketshezi luhlolwa ngokushesha ngaphansi kwesibonakhulu ukubona ukuthi iqanda selitholakele yini. Le nqubo iyaphindaphindwa kuhlu ngalunye oluvuthiwe kuwo womabili amaqanda.

Akuwona wonke ama-follicle aqukethe iqanda ngakho-ke ungamangali uma inani lamaqanda abuyiselwe lingaphansi kwenombolo yama-follicle obukade ubukele athuthuka kwi-ultrasound. Inani elijwayelekile lamaqanda abuyiselwe liphakathi ayisishiyagalombili nantathu futhi inqubo yokubuyisa ihlala cishe imizuzu eyi-20-30.

Okuvame kakhulu, amadoda ahlinzeke ngesampula yomlomo owenziwe ejacured, ngaphambi nje kwenqubo yokubuyisa iqanda. Kwezinye izimo, isidoda ebesikade sibekade sikulondolozwe, isidoda esinikelayo noma isidoda esitholwe ngokuhlinzwa sizosetshenziselwa umanyolo.

Ungazizwa kanjani?

Ngemuva kwenqubo abanye besifazane bangazizwa bethenda kancane esiswini sabo - ibhodlela lamanzi ashisayo lingasiza. Ungahle uzizwe ukhathele ngenxa yokubulala izinzwa. Uzobhekwa amahora ambalwa ngaphambi kokuba uvunyelwe ukuya ekhaya. Ngokulandela inqubo ungaqaphela ukubonwa okuthile okukhanyayo kowesifazane. Lokhu kuyinto ejwayelekile futhi akukho okufanele ukhathazeke ngakho. Kunconywe ukuthi othile akuqhubele ekhaya emtholampilo futhi kungadingeka ukuthi uthathe usuku olulandelayo ungasebenzi ngoba o nobuhlungu obukhulu nokukhathala.

Isigaba 3: Ukutshala kanye Nokuthuthukiswa Kwembambo

Cishe amahora amabili ngaphambi kokubuyiselwa kweqanda, kusampula isampula kumlingani wesilisa. Ukuyekiswa kwezinsuku ezimbili kuya kwezintathu ekuhlukaneni kocansi kukhethwa ngaphambi kosuku lokuqoqa isampula. Isidoda siyabe sesicutshungulwa ukuze kukhethwe isidoda esiqine kakhulu nesisebenza kakhulu. Lokhu kubizwa ngokuthi ukugeza isidoda.

Ukuhlolwa kokutheleleka okuthe xaxa kwabesilisa nabesifazane kuyadingeka ngaphambi kwenqubo ye-IVF ukuvikela ukukhula okuphakathi kungcoliswe. Isitsha esinamaqanda nesidoda sibekwe ku-incubator, ukuvundiswa kuzokwenzeka ngokwemvelo.

Amaqanda afakwa esitsheni esinohlobo lokukhula olukhethekile endaweni yalo. Okuphakathi kuvumela amaqanda nemibungu yakamuva ukuba iqhubeke ikhula njengoba injalo kumashubhu okuwela. Isidoda bese sibekwa kanye namaqanda okufakelwe insubator ukushisa okulinganayo nomzimba wowesifazane.

Omunye wababethuthisi bezingane abahlola amaqanda ngosuku olulandelayo ukuzalanisa. Amaqanda ayahlolwa ngaphansi kwesibonakhulu ukubona ukuthi umanyala wenzekile kanti uzofonelwa ukuthi mangakhi amaqanda akho afakiwe umanyolo. Imibungu ephumela lapho izobe isilungele ukudlulisela esibelethweni ezinsukwini ezimbili kuya kwezinhlanu kamuva.

Uma kwenzeka ngaphansi kwe-ICSI, amaqanda alungiselelwe ukujova futhi ukuvuthwa kwawo kuqinisekisiwe. Isidoda esisodwa sifakwa ngqo kwi-cytoplasm yeqanda - yingakho igama lomjovo we-intra-cytoplasmic isidoda. Umanyolo ungabe usukhonjwa ngendlela efanayo ne-IVF ngemuva kwamahora we-24.

Uma isampula yesidoda ibukeka ijwayelekile, silindele ukuthi ama-70% abe yi-80% amaqanda azovundiswa. Kubalulekile ukwazi ukuthi akuwona wonke amaqabunga ayoqukatha iqanda, akuwona wonke amaqanda ayovundiswa, futhi hhayi wonke iqanda elivunduzisiwe azokwakha umbungu osezingeni elifanele.

Ngesikhathi se-IVF, imibungu yakho ikhehlwa izinsuku ezingaba yisithupha kufigamu elilawulwa amazinga okushisa. Zonke ezinye izinsuku imibungu ihlolwa ngekhwalithi nentuthuko. Lolu lwazi lwabiwe nodokotela ukusiza ukuthola usuku olufanele lokudluliswa kwe-umbungu, okuvame ukuthi kube usuku lwesithathu noma lwesihlanu lwamasiko e-umbungu. Izingcweti zethu zokubeletha zizokushayela ucingo ngemuva kokuhlolwa ngakunye kombungu ukukuvuselela ngekhwalithi ye-umbungu futhi uphendule noma imiphi imibuzo ongaba nayo.

Izigaba Zentuthuko

I-Zygote: Isidoda esisodwa singena eqandeni bese ingqamuzana eliphumela libizwa ngokuthi yi-zygote. I-zygote iqukethe yonke imininingwane yofuzo (i-DNA) edingekayo ukuze ube ngumntwana. Ingxenye yolwazi lofuzo ivela eqandeni likamama nengxenye yesidoda sikababa. i-zygote ichitha izinsuku ezimbalwa ezizayo ihlukanisa ukwenza ibhola lamaseli. Igama elithi cleavage lisetshenziselwa ukuchaza lokhu kuhlukaniswa kweseli.

Morula: Lapho i-zygote ifinyelela i-16 noma amaseli amaningi ibizwa nge- morula. I-morula ayikho enkulu kune-zygote, kepha iyaqhubeka ikhiqiza amaseli amancane namancanyana ngokusebenzisa i-cleavage.

Blastocyst: i-morula iyaqhubeka nokuhlukana, yakha iqembu elingaphakathi lamaseli ngegobolondo elingaphandle. Lesi sigaba sibizwa ngokuthi i -hlambatocyst futhi siqukethe cishe amaseli we-100. Iqembu elingaphakathi lamaseli liba umbungu, ngenkathi iqembu elingaphandle lamaseli lizoba yizitho ezondla futhi zivikele.

Umbungu: I -udingtocyst ifinyelela esibelethweni cishe usuku lwesihlanu, futhi ifake odongeni lwesibeletho cishe ngosuku lwesithupha. Amaseli we-umbungu manje ayanda futhi aqala ukwenza imisebenzi ethile eholela ezinhlotsheni ezahlukahlukene zamaseli ezakha umuntu ongumuntu isib. Amangqamuzana egazi, amaseli ezinso namaseli ezinzwa.

Ukuxoshwa okusiziwe

Enye yezizathu ezivame kakhulu zokuthi umjikelezo we-IVF wehluleke ukuthi umbungu / s wehlulekile ukufakwa. Umbungu kufanele ukhiphe amagobolondo waso ukuze ungene ngaphakathi kwesibeletho. Lokhu kuvame ukwenzeka ezinsukwini ezinhlanu ngemuva kokukhulelwa.

Ngesikhathi sokukhulelwa isidoda kufanele singene kwigobolondo elinzima elizungeze iqanda. Igobolondo eliqinile libizwa ngokuthi i-zona pellucida. Lapho isidoda selungene kwiqanda, i-zona iyaqina futhi ukuvikela noma yisiphi isidoda esengeziwe ukuba singangeni eqandeni. Ngezinsuku ezilandelayo umbungu uthola uchungechunge lwezigaba zokuthuthuka, kusuka ku-zygote kuya ku-morula kuya ku -hlambtocyst. Emvelweni lokhu kuthuthukiswa kwenzeka kumashubhu e-fallopian futhi lapho imibungu ifinyelela esigabeni sokuhlambalaza ishiya ishubhu lokuwa bese ingena esibelethweni sesibeletho.

Ukuze ifakwe ngaphakathi kolwelwesi lwesibeletho, umbungu kufanele ubheke esikhumbeni salo, i-zona pellucida. Uma ukukhahlela kungenzeki umbungu awukwazi ukugxila futhi nokukhulelwa ngeke kwenzeke. Imbangela ejwayelekile yobunzima ngokuqhanyelwa ukuthi igobolondo likhulu noma linzima kakhulu.

Ekusizeni ekubambeni ikhefu elincane lenziwa ku-zona pellucida ukuyenza buthaka ngaphambi nje kokudluliselwa ku -hlambatocyst. Ezimweni ezithile lokhu kubangela ukufakwa okuthe xaxa kwe -hlambatocyst kuyi-endometrium kanye nokwenyuka kwamanani okukhulelwa.

E-Medfem siqasha ukusizakala ezimeni ezinjengobudala obuphambili bokuzala, ukuphakama kwe-FSH, ukuncipha kokugcina ama-ovarian, ukuqina kwe-zona, kanye nokwehluleka kokufakwa kokuqala kokufakwa.

Ukuxilongwa Kwesifo Sofuzo

I-PGD inqubo yokuhlola eyenza sikwazi ukuvivinya imibungu yombhangqwana ophethe uphawu lokuzalwa lwenkinga ethile yesifo esizuze ifa ukuze kukhethwe imibungu enempilo kuphela ukuthi ifakwe esikhundleni / idluliselwe esibelethweni sowesifazane ukuze izame ukufeza ukukhulelwa . Funda kabanzi

Isigaba 4: Ukudluliswa kombungu

Ukudluliswa kombungu kuyinto ekhethekile kakhulu. Izinsuku ezintathu kuya kweziyisihlanu ngemuva kokubuyiselwa kweqanda, umbungu ubekwa emgodleni bese udluliselwa esibelethweni ngokuvuleka kwesitho sangasese sowesifazane. Isibalo semibungu esidluliselwe ngokuya ngeminyaka yowesifazane, imbangela yokuzala, umlando wokukhulelwa, nezinye izinto. Imvamisa imbeleko eyodwa kuya kwemibili ephilile izodluliselwa esibelethweni. Kubalulekile ukuqaphela ukuthi ubungozi bokukhulelwa okuningi bukhuphuka ngenani lemibungu esezingeni elifanele edlulisiwe. Uma kukhona eminye imibungu engeza esezingeni elifanele, ingahle iqandwe ukuze isetshenziswe kamuva. Futhi uzothola izithombe zemibungu yakho edluliselwa kumarekhodi akho.

Le nqubo ithatha kuphela imizuzu embalwa futhi iningi labesifazane alikutholi ukungakhululeki. Ukulandela inqubo uzobe uphumule imizuzu eyi-30 egumbini lethu lokululama bese ukhishwa ukuthi ubuyele ekhaya. Siphakamisa ukuthi ukuthole kulula ngamahora we-24 ngemuva kokudluliswa kwe-embriyo yakho. Ungaqala kabusha umsebenzi olula, ongeyona i-aerobic ezinsukwini ezimbalwa ezizayo. Abesifazane abaningi babuyela emsebenzini ngakusasa uma imisebenzi yabo ingekho nzima.

Isigaba 5: Ukuxhaswa kwesigaba se-Luteal

Isigaba se-Luteal yisikhathi samasonto amabili phakathi kokudluliswa kwe-umbungu nokuhlolwa kokukhulelwa. Ukuqala usuku lwenqubo yokubuyisa amaqanda uzonikezwa iprogesterone ukuze uxhase ukukhulelwa okukhulayo. I-progesterone kungaba ngesimo sama-pessary noma imijovo. Ukuhlolwa kokukhulelwa kwenziwa ezinsukwini ze-14 ngemuva kokudluliswa kwe-umbungu. Ukuqinisekisa ukuhlolwa kokukhulelwa okuhle, sizokuhlelela i-ultrasound amasonto amabili kulandela lezi zivivinyo zokukhulelwa. Kulolu hambo sizofuna ukufakwa kombungu kanye nokuhamba kwenhliziyo kwengane.

Ngokomzwelo lesi isikhathi sokukhokhisa kakhulu. Amazinga ama-Hormone aphezulu futhi akukho okuningi okungenziwa noma okungenakwenziwa ukuthonya umphumela wokwelashwa. Ukuthi ngabe kukhona yini ukukhulelwa okunqunywe ngokomzimba ngemuva nje kokudluliswa kombungu. Kunconywa ukuthi uqalise kabusha imisebenzi ejwayelekile kule nkathi.

Uma kwenzeka ukhulelwe kubalulekile ukuthi uqhubeke nemithi ebinikezwe ngesikhathi sokudluliswa kombungu. Uma kungekho ukukhulelwa kubalulekile ukuxhumana nodokotela wakho. Noma kuzodumaza kakhulu - khumbula ukuthi udokotela wakho uthole imininingwane ebalulekile yokuxilonga kuyo yonke inqubo ezomqondisa ekuhleleni ukwelashwa okuzayo.

Ungazizwa kanjani?

Abanye bethu bathola ukuthi ukuqala ukwelashwa kuyinto enhle ngoba unokuthile okufanele ugxile kukho. Kodwa-ke, abanye bangase besabe ukungenelela ngokomzimba noma bazizwe bedangele kakhulu ukuthi kufanele babhekane nokungenelela.

Ngaphezu kokubhekana nemizwa yokungaqiniseki nokuthuthumela, kanye nethemba, uzobhekana nomthelela wokushintshwa kwama-hormone emzimbeni wakho. Izimpendulo zemithi esetshenzisiwe ziyehluka kakhulu. Abanye besifazane abanazimpawu kanti abanye bazizwa bethambekele kakhulu izinyembezi, ukukhathazeka nokungaxineki. Abanye bazizwa bengakhululekile ngokuqhakaza, ikhanda, ukukhathala nezinye izimpawu. Ngenkathi ungeke usize ngendlela ozizwa ngayo, ngosizo lomeluleki, ungakwazi ukuthola indlela yokulawula kangcono imizwa yakho nokuphendula kwakho ngalezi zikhathi.

Ekuqaleni abesifazane bangayesaba inqubo uqobo, kepha ukulinda imiphumela kuvame ukuba yingxenye enzima kakhulu yokwelashwa. Izinsuku zibonakala zizodlula kancane futhi kungaba yisikhathi sobuthakathaka obukhulu nokuzwela, okwenza kube nzima ukugxila empilweni ejwayelekile.

Sicela uxhumane neMedfem ngepheshana le-IVF / ICSI

Spread uthando

Ngokuqhubeka nokusebenzisa isayithi, uyavuma ukusebenzisa amakhukhi. Ulwazi oluningi

Izilungiselelo zekhukhi kule webhusayithi zibekwe "ukuvumela amakhukhi" ukukunikeza isipiliyoni esihle sokuphequlula kungenzeka. Uma uqhubeka ukusebenzisa lewebhusayithi ngaphandle kokushintsha izilungiselelo zakho ze-cookie noma uchofoze "Yamukela" ngezansi bese uvuma lokhu.

Close