Induction yeOvulation

Yintoni i-ovulation induction?

I-ovulation induction yiprotocol yonyango eyenzelwe ukonyusa inani lamaqanda awafumana ngawo amaqanda kumfazi kumjikelo. Ngelixa ukuvuselelwa kwe-ovarian kwe-IVF kunye ne-ICSI kujolise ekuveliseni amaqanda amaninzi ukuba aqokelele (kubafazi abaqhelekileyo ukuvala i-ovul), ukufunyanwa kwe-ovulation ijolise ekuvuseleleni amaqanda ambalwa kubafazi abangavuseleliyo i-ovul. Unyango luhlala lusetyenziswa kubafazi abane-polycystic ovarian syndrome (PCOS), imeko ebonakaliswa zii-cysts ezininzi ze-ovarian, ixesha elingekho mthethweni okanye lokungabikho komzimba, kunye namaqondo aphezulu amanqanaba endoda (androgen).

Kumjikelo ongacaciswanga (umjikelo wendalo), umfazi uhlala evula iqanda elinye inyanga nganye. Kunqabile kakhulu, ii-ovari zowasetyhini zinokukhupha amaqanda ama-2 kuwo nawuphi na umjikelo, onokuthi ukhokelele kumawele angafaniyo. Kumjikelo ovusayo we-ovulation, injongo kukufezekisa ukukhula okuninzi kunye nokukhutshwa kweqanda -ukukhutshwa kwamaqanda amaninzi kumjikelo omnye. Xa amaqanda aliqela evezwe ngaxeshanye, amathuba okuba akhulelwe ahlala enyuka kakhulu.

Unyango sisifundo sehomoni yokuchuma ukukhulisa ama-ovari ukuba avelise i-follicle evuthiweyo, emva koko ulwalamano lwexesha okanye i-Artificial Insemination (AI) / Intrauterine Insemination (IUI) ukungqinelana ne-ovulation. Kodwa, kuba abantu ababhinqileyo abane-PCOS bahlala bephendula kakhulu kumachiza okuzala, kukho umngcipheko wokwenyani wokuveliswa kweefollicle kunye nokukhulelwa okuninzi. Ukubeka esweni rhoqo kunye nemilinganiselo ye-ultrasound kunye namahomoni ngoko kubalulekile ukuba kuqinisekiswe ukuba inye kuphela okanye ii-follicles ezimbini eziphuhliswayo.

Ukungeniswa kwe-Ovulation kungenziwa kusetyenziswa amayeza angenisiweyo ngomlomo okanye amayeza afakiweyo, kwaye kuhlala kudityaniswa ne-intrauterine insemination (IUI). Izigulana ezinokuthi zixhamle kwi-ovulation induction / IUI zizibini ezinokuchazeka okungachazwanga, i-PCOS, i-endometriosis, kunye nokungasebenzi kakuhle kwe-ovari. Ukuze ube ngumgqatswa wokungeniswa kwe-ovulation kufuneka ube nesisu esiqhelekileyo sesibeleko, ubuncinci ityhubhu enye yesiqhelo, kwaye iqabane lakho kufuneka libe nokubala okuqhelekileyo kwesidoda. Njengelinye lamaziko akhokelayo okuchuma eMzantsi Afrika, ikliniki yaseMedfem Fertility iye yaphatha ngempumelelo abaguli abagqityiweyo nge-ovulation induction ngendlela enoxanduva nesebenzayo. Oku kuthetha ukuba sisebenzisa iiprothokholi ezikhuselekileyo kodwa ezifanelekileyo zokufezekisa amaqondo okuphumelela aphezulu ngelixa sinciphisa umngcipheko woku-odola okuphezulu kokukhulelwa (kathathu okanye nangaphezulu).

Ngubani unyango lwe-ovulation induction?

I-Ovulation induction inokukunceda ukuba:

  • Unengxaki ze-ovulation ezingaphendulanga kumayeza alula
    (ezinje ngeetafile ze-clomiphene).
  • Ukhule ungacacanga kwaye unqwenela ukuzama unyango lwe-ovulation induction ukwenzela ukwandisa inani lamaqanda aveliswayo kumjikelo ngamnye-ngaloo ndlela ukonyusa ithuba lokukhulelwa.

Asebenza njani amachiza okucoca intsholongwane?

Ngexesha lokujikeleza kwendalo ngokwemvelo, ukhupha i-luteinizing hormone (LH) kunye ne-follicle evuselelayo yehomoni (FSH) kwi-pituitary gland. Ezi mahomoni zikhuthaza ukukhula kwefollicle - indawo enamanzi kwindawo ye-ovari apho ikhula khona iqanda. Nangona i-follicles eliqela likhula inyanga nenyanga, kumjikelo wendalo kuphela umntu ovuthiweyo ngokwaneleyo ukuba angaqanda iqanda lakhe.

Kwi-ovulation induction, abasetyhini abangavuli konke konke bathatha i-gonadotropins (iifom ze-FSH kunye / okanye i-LH) ngenaliti ukukhuthaza ukukhula kweqanda elinye okanye nangaphezulu. Ngexesha lonyango lwakho, ugqirha wakho uya kukujonga ngononophelo kwiimvavanyo zegazi kunye nee-ultrasound.

Yintoni endimele ndiyilindele ngexesha lonyango?

Unyango lwakho luhlala luqala ngosuku lwesithathu okanye lwesine kumjikelo wakho wokuya esikhathini kwaye luhlala malunga neentsuku ezisibhozo ukuya kwezilishumi. Umongikazi uyakukufundisa kunye neqabane lakho ukuba ungawanika njani isitofu ekhaya. Uya kuba nokuqeshwa kwiklinikhi ezimbini ukuya kwezine zovavanyo lwegazi kunye / okanye ii-solas zangasese ukubeka esweni impendulo yakho kunye nokulungisa idosi yakho yamayeza.

Ukuqeshwa kwakho kuya kucwangciswa phakathi kwe-7: 30 am kunye ne-9: 00 am, kwaye kuya kubakho rhoqo ukuya kwi-ovulation. Nangona umfazi ngamnye ehlukile, lo ngumzekelo weshedyuli yomjikelo wonyango:

Xa uvavanyo lwegazi kunye nee-phasound zibonisa i-follicles enye ukuya kwezine ezivuthiweyo, omnye woogqirha bethu uya kunika unyango lwesibini (hCG) lokubangela ukuvusa i-ovulation. Ngokuqhelekileyo uya kuvunda i-36 ukuya kwiiyure ezingama-48 emva kwalomjovo wokugqibela.

Phantse i-24 ukuya kwiiyure ezingama-36 emva kwenaliti ye-hCG, uya kuba ne-intrauterine insemination (IUI). Oku kwenziwa ngokufaka isampulu elungiselelwe ngokukodwa isidoda seqabane lakho ngesibeleko kwaye siyibeka kufutshane nasesibelekweni sakho apho inethuba elilungileyo lokuchumisa iqanda. Inkqubo ithatha nje imizuzwana embalwa kwaye ayifanelanga ukuba buhlungu.

Ngaba impumelelo ye-ovulation induction?

Ngokwesiqhelo, i-20% ukuya kwi-25% yezempilo, izibini ezitshatileyo zikhulelwa inyanga nenyanga zizama. Ngokwahlukileyo, umlinganiselo wokukhulelwa phakathi kwabantu abatshatileyo nokungabikho kokuzala uhlala phakathi kwe2% ukuya kwi-10% ngenyanga. Ukufakelwa kwe-ovulation kuvame ukuvelisa amazinga okukhulelwa e-10% ukuya kwi-20% kumjikelo ngamnye, kuxhomekeka kubudala bomfazi, isifo, kunye nexesha lokuzala.

Phakathi kwabasetyhini abanengxaki ethile yokuphazamiseka kwe-ovulatory, unyango lokungenisa i-ovulation lude lubuyisele amaqondo okuchuma aqhelekileyo e-20% kwi-25% ngenyanga. Ukuba awukhulelwe kumjikelo wokuqala wonyango ezintathu siza kuxoxa nawe ngezinye iindlela zonyango.

Ndazi njani ukuba ndiyabhabha?

Ukuba ufumana imijikelezo yokuya esikhathini rhoqo, phantse ngokuqinisekileyo u-ovulating (nokuba ubude bomjikelezo buthini). Ukuqikelela usuku lwe-ovulation, thabatha iintsuku ze-14 ukusuka kumjikelezo ophakathi womjikelezo. Ke ukuba imijikelezo yakho yimihla ye-28, uya kuvuna ngemini ye-14, kodwa ukuba imijikelezo yakho imfutshane, umzekelo, imihla ye-25, ngokuthabatha imihla ye-14, uya kuvunda ngemini ye-11.

Kukho inani leempawu ekufuneka ujonge kuzo xa uzama ukubona ixesha lakho le-ovulation.

I-Mucus: unokubona ithuba kwimfihlo yakho yelungu lobufazi malunga nexesha ukulungele ukuvumba. Kuwo wonke umjikelo wokuya esikhathini, isibeleko okanye ukuvulwa kwesibeleko kuvelisa i-mucus. Kanye ngaphambi kokuba i-ovulation i-mucus icace kwaye ityibilika kwaye ikhangeleka ngathi iluhlaza okweqanda. Lo mbungu unceda isidoda ukuba siye phezulu kwilungu lobufazi nangomlomo wesibeleko.

Iimpawu zangaphambi kokuya esikhathini: Umjikelo wokuya esikhathini uhlala unxulunyaniswa neempawu ezinjengokuqunjelwa sisisu, ububele kunye nokutshintsha kwemvakalelo. Ezi mpawu zihlala zibizwa ngakumbi kubafazi abanengxaki yokuphuma ovumbini, njengaleyo ine-PDCO okanye i-endometriosis.

Iqondo lokushisa: Emva kwe-ovulation iqondo lakho lobushushu liyenyuka kwaye lihlala liphezulu kumjikelezo wonke. Kungenxa yokuba amanqanaba akho eeprogesterone - anceda ukulungiselela i-uterus ukuba ifakwe kwaye ukhulelwe-inyuka nge-ovulation. Kuya kufuneka uthathe ubushushu bakho qho ekuseni. Emva kweenyanga ezimbini ukuya kwezintathu zokurekhoda ubushushu bakho uya kuthembela ukubona ipateni kwaye ukwazi ukumisela usuku lwakho lokuvota. Ngokwesiqhelo kusuku olungaphambi kokuba i-ovulation kukho idiphu kwiqondo lokushisa elibonisa uxinzelelo lwe-LH. Eli lixesha elihle lokuba neentlobano zesini. Kucetyiswa ukuba ulale ngesondo kwiintsuku ezintathu okanye ezine ngaphambi nangomhla wosuku lwakho lokumisa ukuze wandise amathuba okuba ukhulelwe.

Kutheni ndingavuki?

Uninzi lwabasetyhini ubukhulu becala isizathu sokuba bangavuki luvela ngenxa yokudideka kweempawu zehomoni ezivela emzimbeni okuthetha ukuba ukwenzeka kwe-ovulation akunakwenzeka ngendlela eqhelekileyo.

Ukungasebenzi kakuhle kwimeko yesiqhelo ligama elisetyenziselwa ukuchaza iqela leengxaki apho i-ovulation yenzeka khona kwimeko engekazalwa. Ukusilela kwesimo se-pituitary kusetyenziswa xa i-ovulation isilela ukwenzeka kwaphela (isazisi) kwaye akukho zithuba (amenorrhoea). Ngelixa kungekho zimpawu ezithile zesi sifo, kusenokubakho izinto ezithile ezinxulumene noku kubantu abanengxaki yokumitha. Oku kunokubandakanya:

  • I-Amenorrhoea (ukungabikho kokuya esikhathini)
  • Imizila engavumelekanga yokuya esikhathini
  • Ukuya esikhathini
  • ukutyeba
  • Ukuthoba umzimba kakhulu
  • Ukufumana ubunzima obukhulu
  • Ukukhula okungaqhelekanga okanye okukhula kakhulu kweenwele ebusweni nasemzimbeni
  • Acne

Uninzi lwabantu abanemicimbi ye-ovulation banamava e-amenorrohoea. I-amenorrhoea yokuqala yenzeka kumantombazana amantombazana aphantsi kwe-16 engekayi esikhathini, kwaye ihlala ibangelwa kukusilela kwehomoni. I-amenorrhoea yesibini yenzeka kubafazi abakhe bava esikhathini kodwa bayeka ngaphezulu kweenyanga ezintandathu. Oku kunokuhambelana:

  • Ukutyeba kakhulu: Ukuba yi-10 nje ukuya kwi-15% ngaphezu kobunzima bomzimba obufanelekileyo kunokuba negalelo kumngcipheko weengxaki ze-ovulation. Ubunzima obulahlekileyo kubafazi abangavimbiyo buza kubangela ukuba inkqubo eqhelekileyo iqale kwakhona. Ukutyeba ngakumbi kunxulunyaniswa nePCOS.
  • Isifo se-ovari se-Polycystic: I-PCOS yimeko apho amaqanda avuthwa kwii-ovari kodwa engakhutshwa kwii-fallopian tubes kwaye endaweni yoko ahlala kwii-ovari aze akhule abe yi-cysts.
  • I-endometriosis: I-endometriosis yenzeka xa izicubu eziqhele ukujikeleza ngaphakathi kwisibeleko zikhula kwezinye iindawo zomzimba wakho apho zingezizo, njengakwimvumba yeesibeleko, iityhubhu zesifo sokudumba kunye nomphandle wangaphandle wesibeleko. I-endometriosis efumaneka kwi-ovary nayo inokukhula ibe nkulu kwaye ifake ii-cysts ezinokuthi ziphazamisane ne-ovulation.
  • Ukuzivocavoca / ukutyeba kakhulu: Xa umfazi esenza umthambo kakhulu kwaye ukuba umzimba wakhe usezantsi (ngaphantsi kwe-20% yobunzima bomzimba obufanelekileyo, ukuvalwa kwe-ovulation kunokuyeka. Ukuvuswa kunokubuyiselwa ngokubuyela kwimithambo kunye nokutya okunesondlo.
  • Uxinzelelo: Ukudakumba kunye noxinzelelo olunje ngokufelwa ngumntwana kunokubangela impilo yamabhinqa kunye nokuzala kwakhe.
  • Ukungaphumeleli kwe-Ovarian: Oku kukhokelela ekuphulukaneni nokunikezelwa kweqanda ukusuka kwi-ovary ngenxa yokuyeka ukuya esikhathini.
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