KwiVitro Fertilization (IVF)

Yintoni iVitro Fertilisation (IVF)

'IVitro' isuselwa kwisiLatin, 'vitrum', okuthetha iglasi. 'In-vitro fertilization' (IVF) ngokwegama lithetha 'ukuchuma kwiglasi', yiyo loo nto abantwana ababangelwa lolu nyango babizwa ngokuba 'ziintsana zovavanyo'. Yaphuhliswa nangaphezulu kweminyaka ye-30 eyadlulayo kunyango lwabasetyhini abaneebhubhu ezonakalisiweyo zeFallopian, kwaye oku kuhlala kuyisizathu esibalulekileyo sonyango.

Usana lokuqala lwe-IVF emhlabeni uLouise Brown wazalwa e-1978 e-United Kingdom kunye ne-IVF yaba unyango olusemgangathweni lokungakwazi ukuzala ukususela kwi-1983. Ukususela ngoko, ngaphezulu kwe-5 yezigidi zeentsana zizelwe kwihlabathi liphela kwaye izinga lokuphumelela le-IVF ngoku lithelekiseka kwaye lingaphezulu kunelo lendalo. Ugqirha Johan Van Schouwenburg weMedfem Fertility Clinic wenza i-IVF yokuqala eMzantsi Afrika kunye no-Profesa Kruger kwisibhedlele iTygerberg e-1983.


IVF ibhekisa kwindlela yokuncedisa ekuzaleni kwakhona apho iqanda kunye nesidoda kunokuconjululwa ngaphandle komzimba ukuze kwenziwe umbungu. Lo mbungu udluliselwa kwisibeleko ngethemba lokuba uza kufakwa kwaye ukhulelwe.

Lonke unyango lwe-IVF luqala ngenkambo yonyango lwehomoni ukukhuthaza ukukhula kweefollic ezininzi kwi-ovary. Ezi ke ziye zigqobhozwe ngenaliti ekhethekileyo phantsi kwesikhokelo se-ultrasound sokufumana amaqanda, emva koko achunyiswe kwisitya se-petri ('in vitro') ukwenza iimbumba ezininzi. Emva kweentsuku ezintathu ukuya kwezintlanu kwisifumbathisi, inye okanye ezimbini zale mibungu zidluliselwa kwilungu lobufazi ziye esibelekweni, apho ukumiliselwa kwenzeka khona kwaye ukukhulelwa kuqala. Nangona kunjalo, kwi-IVF njengakwindlela yokukhulelwa kwendalo, ayizizo zonke izinto ezifakwayo zembungu zokuba zikhulelwe, yiyo loo nto iimbumba ezingaphezulu ziyekisiwe-ukuze kugqitywe emva koko ukuzama ukuba eyokuqala ayiphumeleli. Umkhenkce ngoku uyinxalenye ebalulekileyo yenkqubo nganye yeklinikhi ye-IVF.

I-Medfem Fertility Clinic yenzisa iiprotocol zokuvuselela ezenzelwe i-IVF ezenziwe ngendlela ethile kwisigulana ngasinye ngokobuninzi bezinto (isifo sokuxilonga, ukukhula, ubunzima / ukuphakama, umphumo womjikelo wangaphambili, imbali yangaphambili yokuzala). Ikliniki yethu ye-IVF iphatha abaguli abangaphezu kwewaka ngonyaka kunye namazinga empumelelo ahlala ethe gqolo kwaye ephezulu ngaphezu kweereyithi zesizwe.

Idosi ephantsi ye-IVF

I-IVF ephantsi ye-IVF, i-IVF encinci yokukhuthaza, yitekhnoloji entsha kunye nephambili yokuzala (i-ART) enikezela ngobumnene obunokubangela ukuvuselelwa kwe-ovari kwindalo ye-vitro fertilization (IVF). Kwi-Low Dose IVF ii-ovari zowesifazane ziyakhuthazwa kancinci, kusetyenziswa iiarhente zokungenisa i-ovulation ngomlomo kunye / okanye idosi ephantsi ye-gonadotropins (i-follicle ekhuthaza i-hormone kunye ne-luteinizing hormone), ukukhuthaza ukukhula kwenani elincinci lamaqanda.

Inkqubo iyafana ne-IVF yemveli, ngaphandle kokuba injongo kukwenza kuphela iimbumba ezimbalwa kodwa ezikumgangatho ophezulu zothumelo. I-IVF ephantsi yethamo liphendula izinto ezimbini ezixhalabisayo kwizigulana kunye neendleko zogqirha kunye nokuzinyameka. Imikhwa yamva nje kwicandelo lokuchuma ikhetha ukufakwa kwe-ovulation esebenzisa amayeza ambalwa kwaye ivelise imibungu embalwa kodwa esemgangathweni kune-induction ovulation esebenzisa idosi ephezulu kakhulu yamayeza. Ngamanye amagama, i-IVF ephantsi ye-IVF yindlela efanelekileyo enokusetyenziswa ukunceda abasetyhini ukuba bakhulelwe ngomngcipheko omncinci kunye neendleko eziphantsi.

Idosi ephantsi ye-IVF sisixhobo esihle kakhulu se-ART esidibanisa umsantsa phakathi kwe-Natural Cycle IVF kunye ne-IVF yesiko. Ngelixa kumjikelo we-IVF wendalo akukho kukhuthazwa kwe-ovari kwenziwa (akukho mayeza athethwayo kunye / okanye atofwayo), ngesiqhelo avelisa kuphela amaqanda ayi-1-2 akhuliswe ngokwendalo kunye nombungu omnye, kwi-Low Dose IVF i-ovarian "ethambileyo" evuselela amaqanda ama-3-4 kunye neembumba ezingama-2-3, ezonyusa ukusebenza ngokukuko komjikelo. Ngelixa kwi-IVF yendabuko idosi ephezulu ye-gonadotropins ihlala isetyenziselwa ukwandisa amaqanda / iimbungu ezivela kumjikelo omnye, kwi-Low Dose IVF liqanda kunye nomgangatho wombungu owonyuswe endaweni yenani.

Isetyenziswa nini i-IVF?

I-IVF kwasekuqaleni yayenzelwe abasetyhini abaneebhubhu ezivaliweyo zokuwa okanye ezingasasebenziyo kwaye isasetyenziselwa ukunyanga le meko. Isetyenziswe xa ukungacoceki kungachazwa kwaye kwezi zizathu zilandelayo ze-ovulatory okanye ulwakhiwo:

  • Iingxaki zesibeleko
  • Endometriosis
  • Ukusilela kwe-IUI
  • Iifibroids
  • Into yokungafezeki kwabesilisa
  • Iingxaki ze-ovulation
  • I-Polycystic ovarian syndrome
  • Ukungakwazi ukuchazwa

Amanqanaba e-IVF

Ukuqala i-IVF kunokuba lixesha elinomdla kakhulu - lelinye inyathelo elisondele lokuba ngumzali. Ngokwemvelo uya kuziva unethemba ngesiphumo esiphumelelayo kodwa kuya kufuneka uzilungiselele malunga neenyanga ezimbini zamayeza, iinkqubo ezahlukeneyo kunye novavanyo. Izinga lokuphumelela le-IVF liphezulu, kodwa uninzi lwabantu abatshatileyo imijikelezo yonyango emininzi iyafuneka.

Amanqanaba asisiseko achaphazelekayo kwinkqubo ye-IVF acacisiwe apha ngezantsi. Yonke inkqubo ukusukela ekuqalisweni kokuvuselelwa kwe-ovari ukuya kwinqanaba lokudluliselwa kwe-umbungu ihlala ithatha nje iiveki ezintathu.

Uxinzelelo kangakanani IVF

IVF ayisiyonto eyodwa kodwa kunokuba ibe luchungechunge lwamanqanaba ekufuneka ngalinye ligqitywe ngaphambi kokuwisa olandelayo. Oku kunokwenza kube yinkqubo yokuchitha ixesha elininzi. Isibini sinokuhamba kuluhlu lweemvakalelo ezinzulu. Iimpazamo zinokuhamba usuka ethembeni uye kuloyiko, ukusuka kulonwabo ukuya ekuphoxekeni. Abasetyhini abaninzi bachaza amava okuhlangabezana nokungachumeki kunye nonyango lwe-IVF njenge- "rollercoaster" yeemvakalelo. Unokuziva amaxesha onxunguphalo olukhulu, umsindo okanye ukheswa ngeli xesha. Amava akho kunye nendlela ojamelana ngayo iya kuxhomekeka kwinani elikhulu lezinto ezizodwa kubandakanya ubuntu bakho, inethiwekhi yakho yenkxaso, ubudlelwane onabo neqabane lakho, indlela osabela ngayo kumayeza okuchuma kunye nobude nenani lemijikelezo ye-IVF oya kuyo .

Kuyinto eqhelekileyo ukuziva unxunguphele, kodwa unokwenza izinto ezininzi ukukhathalela impilo yakho ngokweemvakalelo. Kubalulekile ukuba uzinike ixesha lokuphumla kunye nokuchacha kumjikelo ngamnye wonyango. Kuya kufuneka wamkele utshintsho oluziswa yi-IVF emzimbeni wakho, utshintsho olwenzeka kumanqanaba amandla akho, kwaye kuya kufuneka uzame ukunciphisa okanye ukubeka phambili imisebenzi yakho ngokufanelekileyo.

IMedfem Fertility Clinic inikezela ngeenkonzo zokucebisa ngokuzala ngokusebenzisa iqabane lethu uGqirha Mandy Rodrigues. Sincoma kakhulu ukuba wonke umntu oqala umjikelo we-IVF afune ukuxhaswa ngugqirha wezengqondo onamava novelwano. Amanqanaba oxinzelelo olwehlisiweyo kunye nenkqubo elungileyo yenkxaso iyaziwa ukuba yonyusa isiphumo sokukhulelwa.

Imiphumela

Esona siphumo sixhaphake ngokubanzi 'esinxulumene ne-IVF kukukhulelwa okuninzi. Kukwakho nomngcipheko omncinci kakhulu wokuba abanye abantu basetyhini (1-2%) baphinde baphendule kumachiza e-hormone asetyenziselwa ukukhuthaza ii-ovari, kodwa ukubeka esweni i-ultrasound kunye ne-hormone ngeli nqanaba lonyango lweziyobisi zihlala ziqinisekisa ukuba nakuphi na ukuphendula okungaphezulu kuyajongwa kwaye nabuphi na ubungozi obunokuthintelwa. Ukuqokelelwa kweqanda kunokungonwabi, kwaye kuyenziwa nge-sedation eyaziwayo. Banikwe ababulali beentlungu abafanelekileyo kubo bonke ukuba kukho imfuneko yokuthatha.

I-Ovarian Hyperstimulation Syndrome (OHSS) yeyona nto inqabileyo kodwa enokubeka ubomi esichengeni kwimeko yezempilo enokuthi yenzeke xa ama-ovary akho ekhuthazwe kakhulu ngamayeza okuchuma. Ama-ovari anokukhula ngobukhulu kwaye avelise amanzi amakhulu. Luphawulwa ziintlungu kunye nokuqhakaza esiswini sakho kwaye ukuba isiqaqa sinokubangela iingxaki ngokuphefumla okanye ngokuchama. Nxibelelana nelungu leqela lakho lezempilo ngokukhawuleza ukuba uyakholelwa ukuba unazo naziphi na ezi mpawu.

Ukuphucula amathuba aKho

Ubunzima: Kubalulekile ukuba kubunzima obunempilo bokuphakama kwakho. Abasetyhini abanesalathiso sobunzima bomzimba abangaphantsi kwe-19 okanye ngaphezulu kwama-32 banethuba elisezantsi lokukhulelwa kunye nomngcipheko owandayo wokuphuma kwesisu.

Ukutshaya: Abafazi abatshayayo banamathuba aphantsi okuba bakhulelwe kunye neqondo eliphakamileyo lokungahambi kakuhle.

Izixhasi: Sicebisa ukuba uthathe i-multivitamin equkethe i-folic acid (i-0.4 ukuya kwi-1.0 mg imihla ngemihla). Le Vitamin ye-B inciphisa umngcipheko weziphene ezithile zobuchopho kunye nomqolo wesibeleko.

IiNtlawulo zeNtuthuko

Njengolunye uhlobo lonyango lokuchuma, amaqondo okuphumelela kwi-IVF ukwehla nje xa izigulana zifikelela kwiminyaka engama-35 okanye njalo. Ngaphambi koko, amaxabiso okukhulelwa e-IVF kwiklinikhi yokuChuma kweMedfem ijikeleze i-50%. Kubalulekile ukuqonda intsingiselo yempumelelo kwaye ngoku ngoku kusetyenziswa inqanaba "lokuzalwa", ithuba lokuzala umntwana osempilweni. IMedfem Fertility Clinic inezinga lempumelelo elingqinelanayo nelona liphezulu lixeliweyo kwiiklinikhi kwihlabathi liphela.

Umsebenzi waselebhu

Intracytoplasmic sperm injin (I-ICSI) yindlela apho isidoda esinye sibekwa kwiqanda. I-ICSI yeyona inkqubela phambili kunyango lwenzalo ukususwa kwenkqubo yokuchumisa i-vitro (IVF) kwaye ivumele amadoda amaninzi ukuba abe nabantwana abanxulumene nemfuza. Kuba i-ICSI ifuna isidoda esimbalwa kakhulu, inokuba lonyango olusebenzayo kumadoda aneempawu ezixhaphakileyo zesidoda. Ngokwesiqhelo, i-ICSI isebenzisa isidoda esijijekileyo, kodwa isidoda esibuyiselweyo siyasetyenziswa. I-ICSI yenziwa njengenxalenye yomjikelo we-IVF.

I-Laser incedise ukuKhangelwa: Kwinkqubo yesiqhelo yokumiliselwa kombungu kufuneka ugqobhoze isambatho sangaphandle esifana nejel esibizwa ngokuba yi-zona pellucida ngaphambi kokuncamathela kwi-endometrium. Ezinye iimbumba zinokuba ne-zona pellucida eqinileyo kunezinye. Kuyenzeka ukuba uvule encinci kwi-zona pellucida usebenzisa i-laser, ngaphambi nje kokudluliselwa kwembungu. Obu buchule bubizwa ngokuba kukuqanduselwa kwelaser. Yinto eqhelekileyo kwiklinikhi yaseMedfem kwizigulana ezingaphezulu kweminyaka yobudala be-38.

Inkcubeko ye-Blastocyst isetyenziselwa ukugcina ukukhula kombungu kwelebhu ngaphezulu kweentsuku ezintathu. Emva kweentsuku ezintlanu kwinkcubeko, imibungu ifikelela kwinqanaba lokuhlambela, apho ineeseli ezingaphezulu kwe-80 ezijikeleze umjelo ophakathi ogcwele amanzi. Eli xesha lide lenkcubeko ye-umbungu livumela amandla aphucukileyo okukhetha imibungu esempilweni yokudluliselwa kwaye inxulunyaniswa nenqanaba eliphezulu lokukhulelwa, ngelixa kudluliswa imibungu embalwa.

Ukuveliswa kwe-embryo: Ukufukula umbungu unokuhlala emva komjikelezo we-in vitro fertilization (IVF) kunye nokutshintshwa kombungu omtsha. Le mibungu inokuba ifanelekile ukuba ikwazi ukugcina amanzi okanye ikhephu. I-embopyo cryopreservation inikezela ithuba lokuzama okongeziweyo xa ukhulelwe ukusuka kumjikelo omnye we-IVF. IVitrification yindlela ekhethekileyo yokubandisa apho imibungu iyilahlwa isebenzisa ubuchwephesha bokupholisa ngokukhawuleza, ukubenza bube yingqimba yeglasi endaweni yomkhenkce, kwaye ngokwenza oko kuthintela ukwakheka kwe-ice-crystal okunokuba yingozi kakhulu ekusindeni kwabo.


Amanqanaba e-IVF

Inqanaba 1: Ukukhuthaza kunye nokubeka esweni u-Ovarian

Ekuqaleni komjikelo wakho wokuya esikhathini i-hypothalamus ikhupha i-hormone ebizwa ngokuba yi-gonadtrophin-ukukhulula i-hormone (GnRH). I-GnRH yona ibangela ukuba i-pituitary gland ikhuphe i-hormone ebizwa ngokuba yi-follicle ivuselela i-hormone (FSH) ukulungiselela iqanda ukuba ikhuphe. Xa iqanda liqolile, i-pituitary gland ivelisa enye i-hormone ebizwa ngokuba yi-luteinising hormone (LH). Oku kukhuthaza i-follicle ukuba ikhuphe iqanda kwi-fallopian tube kwinkqubo eyaziwa ngokuba yi-ovulation. Iifollic zingamanzi azaliswe zii-sacs apho amaqanda akhula khona ekukhuleni.

Nge-IVF, amayeza athile asetyenziswa ukukhusela ukukhutshwa kwamaqanda kwangoko ngelixa amanye amayeza, inguqulelo eyenziweyo ye-FSH, esetyenziselwa ukukhuthaza ama-ovari ukuphuhlisa ii-follicles ze-ovarian. Ngamaqanda amaninzi aqolileyo afumanekayo ngokuzama ukuchumisa kunye nokudluliselwa kuthenjwa ukuba ubuncinci kuya kubangela ukukhulelwa.

Kwisigaba sokunyusa i-ovari, ii-ovaries zakho ziyakhuthazeka ukuba zivelise amaqanda amaninzi kunesiqhelo. Uya kuthatha imijovo yemihla ngemihla yehomoni ye-luteinizing (LH) kunye ne-follicle evuselelayo yehomoni (FSH) malunga ne-8 ukuya kwiintsuku ze-10. La machiza e-hormone aya kukhuthaza ii-ovaries zakho ukuba zivelise ii-follicles ezininzi, nganye kuzo inokuba neqanda. Omnye wabongikazi bethu uya kukufundisa ukuba uzinike njani ngokwakho isitofu.

Iindidi ezimbini zamayeza asetyenziswa ngeli nqanaba ukucinezela i-ovulation:

  • I-Cetrotide yongezwa njengesixhobo sokufaka intsholongwane kanye emva kokuba ifollicle ifike malunga ne-14mm ngobukhulu kwiprotocol eyaziwayo. Oku kwaziwa njenge protocol yomchasi kwaye iqala ngomhla wesithathu wokuya esikhathini.
  • Kwi-Long Course Protocol iyeza elibizwa ngokuba nguLucrin liqaliswa ngokuqengqelekayo kususela kumhla wokuqala wamashumi amabini okuqala komjikelo wokuya esikhathini ukuthintela i-ovulation yeefliclic evuselelweyo. Nje ukuba ixesha liqale i-FSH kunye ne-LH sele iqalile ukukhuthaza ukukhula kwef follicle njengakwenye inkqubo.

Ngexesha lokukhuthaza i-ovarian sisebenzisa i-ultrasound ukubeka esweni ii-ovaries zakho, kunye novavanyo lwegazi ukumisela amanqanaba akho e-estrogen. Izikhuseli ze-Ultrasound zenziwa emva kweentsuku ezintlanu zokufakwa inaliti yehomoni ukumisela inani leefollicle kunye nobungakanani be follicle. Ayizizo zonke ii-follicle eziqukethe amaqanda kunye nobungakanani be-follicle ezichaza ukukhula kwamaqanda. Ngokwesiqhelo ii-follicles zincinci kwiskena sokuqala, izikena ezilandelayo kunye nenaliti yehomoni iya kuqhubeka de ifollicle ekhokelayo ifikelele kwi-18mm okanye ngaphezulu ubukhulu.

Inaliti ye-Ovulation (i-Ovitrelle okanye i-Lucrin) -Lenaliti ihlala inikwa ngexesha elithile ngorhatya. Ukufunyanwa kwakhona kweqanda kuya kuthi emva kweeyure ezingama-36 kwenziwe njalo emva kwenaliti ye-ovulation.

Uya kuba novavanyo lwe-phasound yakho kunye novavanyo lwegazi olwenziwe kwiKliniki ye-Fertility Fertility phakathi kwe-7: 00 am kunye ne-9: 30 am ngoMvulo ukuya ngoLwesihlanu, naphakathi kwe7: 30 am kunye ne9: 00 am ngeempelaveki.

Inqanaba 2: Ukubuyiswa kweqanda (i-oocyte)

Nje ukuba i-ultrasound kunye novavanyo lwegazi lubonise ukuba unobungakanani obufanelekileyo kunye nenani leefollicle, uya kuthatha inaliti ye-hCG (iChorionic Gonadotropin yabantu) yokuvuselela uvutho lokugqibela lwamaqanda. Ukubuyiselwa kweqanda kulungiswe ngaphambi nje kokulindela i-ovulation, ngokufuthi iiyure ze-36 emva kolawulo lwe-ovulation inducing drug. Ugqirha wakho uya kuzama ukubuyisa amaqanda amaninzi aqolileyo njengoko kunokwenzeka.

Ukubuyiselwa kweqanda kwenziwa phantsi kwe-anesthetic yendawo, ehlala ixhaphakileyo ngenaliti ekhokelwa yi-ultrasound. Iifollicle ezivuthiweyo zichongiwe zisebenzisa i-ultrasound, emva koko inaliti idluliselwa kudonga lobufazi kwi-follicle kunye nolwelo olukhutshwe kwi-follicle evuthiweyo ngokufunxa kakuhle. Ubulwelo buhlolwa kwangoko phantsi kwemicroscope ukubona ukuba iqanda lihlaziyiwe na. Inkqubo iphindaphindwe kwi-follicle nganye evuthiweyo kumanqatha amabini.

Ayizizo zonke iifollicle eziqukethe iqanda ukuze ungamangalisi ukuba inani lamaqanda abuyiselweyo lingaphantsi kwenani leefollicle obukade ubukele ziphuhliswa kwi-ultrasound. Inani eliqhelekileyo lamaqanda abuyiselweyo liphakathi kwesibhozo kwaye intle kwaye inkqubo yokubuyisa ihlala malunga nemizuzu ye-20-30.

Eyona nto ixhaphakileyo, amadoda aya kubonelela ngesampula yokukhupha isidoda ukuze isetyenziswe, ngaphambi kwenkqubo yokubuyisa iqanda. Kwezinye iimeko, isidala ebesikhutshelwe ngaphambili, isidoda esifakileyo okanye isidoda esibuyiselweyo siya kusetyenziselwa isichumiso.

Uziva njani?

Emva kwenkqubo abanye basetyhini banokuziva ithenda elincinci esiswini sabo - ibhotile yamanzi ashushu anokunceda. Unokuziva udiniwe ngenxa ye-anesthetic. Uya kubekwa esweni iiyure ezimbalwa ngaphambi kokuba uvunyelwe ukuba ugoduke. Ukulandela inkqubo unokuphawula ukukhanya okubonayo kobufazi. Le yinto eqhelekileyo kwaye akukho nto yakhathazeka ngayo. Kuyacetyiswa ukuba umntu akuqhubele ekhaya ekliniki kwaye kungafuneka uthathe usuku olulandelayo ungahambi emsebenzini ngenxa yeentlungu ezincinci kunye nokukhathala.

Inqanaba 3: Ukuchumisa kunye nokuPhuhlisa umbungu

Malunga neeyure ezimbini ngaphambi kokufunyanwa kweqanda, isampulu yamaduna iqokelelwa kwiqabane lobudoda. Iintsuku ezimbini ukuya kwezintathu zokuyeka ukubonana ngesondo kukhethwa ngaphambi komhla wokuqokelelwa kwesampula. Isidoda ke siyalungiswa ukuze kukhethwe esona soda someleleyo nesona sisebenzayo. Oku kubizwa ngokuba kukuhlanjwa isidoda.

Iimvavanyo ezosulelayo zokusuleleka kumadoda nabasetyhini ziyafuneka ngaphambi kwenkqubo ye-IVF ukuthintela ukukhula kungangcoliseki. Isitya esinamaqanda kunye nesidoda sibekwe kwi-incubator, ukuchumisa kuya kwenzeka ngokwemvelo.

Amaqanda abekwe kwisitya esinendawo ekhethekileyo yokukhula kwindawo. Esona sithuba sivumela amaqanda kunye nee-embrios kamva ukuba ziqhubeke nokukhula njengoko zinokwenzeka kwiisubopian tubes. Isidoda ke siye sibekwe kumaqanda ayo afakwe kwi-incubator kwiqondo lokushisa lomzimba womfazi.

Omnye woochwephesha bethu abavavanya amaqanda ngemini elandelayo ukuze bachume. Amaqanda ayavavanywa phantsi kwemicroscope ukufumanisa ukuba ngaba isichumiso senzekile na kwaye uya kufowunelwa malunga nokuba mangaphi amaqanda akho achumileyo. I-embusos enokubakho iya kuba ilungele ukugqithisela kwisibeleko emva kweentsuku ezimbini ukuya kwezintlanu.

Ukuba uphantsi kwe-ICSI, amaqanda alungiselelwe inaliti kunye nokuvuthwa kwawo kuqinisekisiwe. Isidoda esinye sibekwa ngokuthe ngqo kwi-cytoplasm yeqanda - ngenxa yoko igama lesitayile se-intra-cytoplasmic sperm. Ukuchumisa kunokuchongwa ngendlela efanayo nakwi-IVF emva kweeyure ze-24.

Ukuba isampulu yesidoda ikhangeleka iqhelekile, silindele malunga ne-70% ukuya kwi-80% yamaqanda ukuba aqanduselwe. Kubalulekile ukwazi ukuba ayizizo zonke ii-follicle eziya kuba neqanda, hayi onke amaqanda aya kwenziwa isichumiso, kwaye ayisiyiyo yonke iqanda elichumileyo eliya kuqhubeka isenza isidumbu esifanelekileyo.

Ngexesha le-IVF, imibungu yakho ikhahlelwa kangangeentsuku ezintandathu kwisibambiso esilawulwa bubushushu. Yonke imihla eminye imibungu ihlolwa ngomgangatho kunye nophuhliso. Olu lwazi kwabelwana ngalo ngoogqirha ukunceda ukumisela umhla ofanelekileyo wokudluliselwa kwe-umbungu, oqhele ukuba lusuku lwesithathu okanye usuku lwenkcubeko ye-umbungu. Iingcali ze-embryologists zethu ziya kukufowunela emva kovavanyo ngalunye lweemveku ukukuhlaziya kumgangatho wombungu kunye nokuphendula nayiphi na imibuzo onokuba unayo.

Amanqanaba oPhuculo

I-Zygote: Isidoda esinye singena kwiqanda kwaye iseli ebangelwa yiyo ibizwa ngokuba yi-zygote. I-zygote iqulethe lonke ulwazi lwofuzo (i-DNA) oluyimfuneko ukuze ube ngumntwana. Isiqingatha solwazi lwemfuzo sivela kwiqanda lomama kunye nesiqingatha kwisidoda sikatata. I-zygote ichitha iintsuku ezimbalwa ezizayo zokwahlulahlula ukwenza ibhola yeeseli. Igama elithi cleavage lisetyenziswa ukuchaza olu hlaselo lweeseli.

Morula: Xa i-zygote ifikelela kwi-16 okanye iiseli ezingaphezulu ibizwa ngokuba yi-morula. Isimilo asikho sikhulu kune-yazgote, kodwa sihlala sivelisa iiseli ezincinci nezincinci ngokusebenzisa i-cleavage.

Blastocyst: I-morula iyaqhubeka nokuhlukana, isenza iqela elingaphakathi leeseli ngeqokobhe langaphandle. Eli nqanaba libizwa ngokuba yi-tlhotocyst kwaye iqulathe iiseli ze-100. Iqela langaphakathi leeseli liya kuba yimbungu, ngelixa iqela elingaphandle leeseli liya kuba ziimpawu ezondla kwaye zikukhusele.

Umbungu: I-ebuswenitocyst ifikelela kwisibeleko malunga nemihla emihlanu, kwaye ifakwe eludongeni lwesibeleko malunga nomhla wesithandathu. Iiseli ze-embryo ngoku ziphindaphindeka kwaye ziqala ukuthatha imisebenzi ethile ekhokelela kwiindidi ezahlukeneyo zeeseli ezenza umntu ongumntu, umzekelo: iiseli zegazi, iiseli zezintso kunye neeseli zemithambo.

Ukuncedisa ukuHatching

Esinye sezizathu ezixhaphakileyo zokuba umjikelo we-IVF ungaphumeleli kungenxa yokuba ii-umbungu zisilele ukumiliselwa. Umbungu kufuneka ubambe iqokobhe lakhe ukuze ungene ngaphakathi kwesibeleko. Oku kuhlala kwenzeka kwiintsuku ezintlanu emva kokuchumisa.

Ngexesha lokuchumisa isidoda kufuneka singene kwiqokobhe elilukhuni elijikeleze iqanda. Eliqokobhe lilukhuni libizwa ngokuba yi-zona pellucida. Nje ukuba isidoda singene kwiqanda, i-zona ilukhuni kwakhona ukuthintela nasiphi na isidoda esongezelelweyo ukuba singangeni kwiqanda. Ngezi ntsuku zilandelayo umbungu uphantsi kwamanqanaba ophuhliso, ukusuka kwi-zygote ukuya kwi-morula ukuya kwi-tlhotocyst. Kwindalo le ntsingiselo yenzeka kwiityhubhu ze-fallopian kwaye xa imibungu ifikelela kwinqanaba lokuhlambalaza bayishiya ityhubhu ye-fallopian kwaye bangene kwi-uterine patity.

Ukulungiselela ukungena ngaphakathi kwi-uterine lining, umbungu kufuneka ukhuphe kwiqokobhe lakhe, i-zona pellucida. Ukuba akuqeshwanga akwenzeki ukuba umbungu ungangenisi kwaye ukhulelwe ngekhe kwenzeke. Unobangela oqhelekileyo wobunzima ngokuhombeka kukuba iqokobhe likhulu kakhulu okanye linzima kakhulu.

Kwi-hatching encinci ikhefu elincinci lenziwa kwi-zona pellucida ukuyenza buthathaka ngaphambi nje kokutshintshwa ngokuhlambalaza. Kwiimeko ezithile oku kuphumela ekufakweni okuphezulu kwe -hlambatocyst kwi-endometrium kunye nokunyuka kwamanani okukhulelwa.

EMedfem sisebenzisa ukuqeshisa ngokuncedayo kwiimeko ezinje ngobudala bokuzala, ukuphakama kwe-FSH, ukuhla kwe-ovarian, ukuqina kwe-zona, kunye nokusilela kwangaphambi kokufakwa.

Ukuxilongwa kwesifo sofuzo

I-PGD yinkqubo yovavanyo esenza ukuba sikwazi ukuvavanya imibungu yesibini esiphethe uphawu lwofuzo kwisifo esithile esikhoyo ukuze kukhethwe kuphela imibungu enempilo ukuba itshintshwe / idluliselwe kwisibeleko somfazi ukuze azame ukufezekisa ukukhulelwa. . Funda ngokugqithisileyo

Inqanaba 4: Ukudluliselwa kwe-Embryo

Ukudluliselwa kweembungu ngamava akhethekileyo. Iintsuku ezintathu ukuya kwezihlanu emva kokufunyanwa kweqanda, umbungu ubekwa kwi-catheter kwaye udluliselwe kwisibeleko ngokuvulwa kwelungu lobufazi. Inani le-embryos elidluliselwe lixhomekeke kubudala bukasetyhini, unobangela wokuzala, imbali yokukhulelwa, kunye nezinye izinto. Ngokubanzi enye ukuya kwezimbini zezona ntlobo zisempilweni ziya kugqithiselwa kwisibeleko. Kubalulekile ukuba uqaphele ukuba umngcipheko wokukhulelwa okuninzi ukwanda ngenani leemveku ezisemgangathweni ezidlulisiweyo. Ukuba kukho nayiphi na imibungu eyongeziweyo esemgangathweni osemgangathweni, inokuba shushu ukuze isetyenziswe kamva. Uya kufumana kwakhona imifanekiso yemibungu yakho etshintshelwa kwiirekhodi zakho.

Le nkqubo ithatha kuphela imizuzu embalwa kwaye uninzi lwamabhinqa alufumani ukuba lungathandeki. Ukulandela inkqubo uya kuphumla imizuzu ye-30 kwigumbi lethu lokubuyisela kwaye ke uya kukhululwa ukuba ugoduke. Siphakamisa ukuba uthathe lula kwiiyure ze-24 emva kokudluliselwa kwe-umbungu. Ungaqala kwakhona umsebenzi wokukhanya, ongeyi-aerobic kwiintsuku ezimbalwa ezizayo. Abafazi abaninzi babuyela emsebenzini ngosuku olulandelayo ukuba imisebenzi yabo ayinzima.

Inqanaba 5: Inqanaba lesigaba seLuteal

Isigaba se-Luteal sisithuba seveki ezimbini phakathi kokudluliselwa kwe-umbungu kunye novavanyo lokukhulelwa. Ukuqala komhla wenkqubo yokubuyisa iqanda uya kuthi ubekelwe iprogesterone ukuze kuxhaswe ukukhulelwa okukhulayo. Iprogesterone inokuba yimo yeepessaries okanye inaliti. Uvavanyo lokukhulelwa lwenziwa kwiintsuku ze-14 emva kokudluliselwa kwe-umbungu. Ukuqinisekisa uvavanyo lokukhulelwa okuqinisekileyo, siya kucwangcisa i-ultrasound kwiiveki ezimbini ezilandela ezi mvavanyo zokukhulelwa. Kolu tyelelo sizakujongana nokufakelwa kombungu kunye nokuhamba kwentliziyo.

Ngokweemvakalelo eli lixesha lokuhlawulisa kakhulu. Amanqanaba ama-Hormone aphezulu kwaye akukho kuninzi okunokwenziwa okanye kungenakwenziwa ukuphembelela kwiziphumo zonyango. Nokuba kukho ukukhulelwa kuqinisekisiwe ngokwasemzimbeni emva nje kokudluliselwa kweembungu. Kucetyiswa ukuba uqalise ukwenza imisebenzi yesiqhelo ngeli xesha.

Kwimeko yokukhulelwa kubalulekile ukuba uqhubeke kunyango ebelumiselwe ngexesha lokudluliselwa kwembungu. Ukuba akukho kumitha kubalulekile ukunxibelelana nogqirha wakho. Nangona iyakudanisa kakhulu-khumbula ukuba ugqirha wakho ufumene ulwazi oluxabisekileyo lokuqonda kwinkqubo yonke eya kumkhokela ekucwangciseni unyango lwexesha elizayo.

Uziva njani?

Abanye bethu bafumanisa ukuba ukuqala unyango ngamava afanelekileyo kuba unento ekufuneka ugxile kuyo. Nangona kunjalo, abanye banokoyika ukungenelela komzimba okanye bazive bephoxekile kakhulu ukuba kufuneka bajongane nongenelelo.

Ukongeza ekujonganeni neemvakalelo zokungaqiniseki kunye noxinzelelo, kunye nethemba, uya kujongana nefuthe lotshintsho lwehomoni emzimbeni wakho. Iimpendulo kumayeza asetyenzisiweyo ayahluka kakhulu. Abanye abantu basetyhini abanazo iimpawu ngelixa abanye beziva benemvakalelo kwaye bathanda kakhulu ukulila, ukuxhalaba kunye nokungakhathali. Abanye baziva bengakhululekanga ngokuqunjelwa, intloko ebuhlungu, ukudinwa kunye nezinye iimpawu. Ngelixa ungakwazi ukunceda indlela oziva ngayo, ngoncedo lomcebisi, unokufumana indlela yokulawula ngcono iimvakalelo zakho kunye nokuphendula kwakho ngala maxesha.

Ekuqaleni abantu basetyhini banokoyika eyona nkqubo, kodwa ukulinda iziphumo kuyeyona nto inzima kunyango. Iintsuku zibonakala zidlula kancinci kwaye kunokuba lixesha lokuba sesichengeni kakhulu nokuziva uziva, kwenza ukuba kube nzima ukugxila kubomi obuqhelekileyo.

Nceda unxibelelane neMedfem yencwadana ye-IVF / ICSI

Ukusabalalisa uthando

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